BLACKSBURG, Va., July 9, 2011 - The Core Laboratory Facility at the Virginia Bioinformatics Institute at Virginia Tech has installed Ion Torrent’s new, state-of-the-art Personal Genome Machine™, adding revolutionary semiconductor sequencing technology to its cutting edge Next Generation Sequencing services.

Ion Torrent pairs semiconductor technology with a basic, well-characterized biochemical process to perform massively parallel sequencing without using the light-releasing reactions and sensitive cameras required for other sequencing platforms. This provides a direct link between chemical and digital data, allowing for a fast, scalable sequencing solution at an affordable price.

Acquisition of the PGM™ system strengthens the Core Laboratory’s reputation as a one-stop shop for all sequencing applications. Ion Torrent boasts one of the fastest workflows around, making it possible to fully prepare eight samples in less than six hours. The Personal Genome Machine™ is capable of producing more than 10 megabases of data with read lengths of up to 200 base pairs in a single two-hour sequencing run, allowing researchers to rapidly and inexpensively bridge the gap between hypotheses and results. Multiplex amplicon, transcriptome, and small RNA sequencing are ideal for the PGM™ sequencer, and it is fully compatible with applications such as paired-end sequencing, ChIP-Seq, and methylation. Ion Torrent service offerings in the Core Laboratory Facility place the VBI on the leading edge of the next wave of sequencing technology.

VBI acknowledges the administrative and individual support that made the acquisition of the PGM™ system possible:

Adminstrative Support
The College of Agriculture and Life Sciences through the SCHEV Equipment Trust Fund Program
The Fralin Life Science Institute (Director Dennis Dean, Ph.D.)
The Department of Biochemistry (Chair Peter Kennelly, Ph.D.)
The Department of Entomology (Chair Loke Kok, Ph.D.)

Individual Support
Igor Sharakhov, Ph.D. (Entomology)
Zach Adelman, Ph.D. (Entomology)
Kevin Myles, Ph.D. (Entomology)
Jake Tu, Ph.D. (Biochemistry)
Jinsong Zhu, Ph.D. (Biochemistry)

About the Virginia Bioinformatics Institute
The Virginia Bioinformatics Institute at Virginia Tech is a premier bioinformatics, computational biology, and systems biology research facility that uses transdisciplinary approaches to science combining information technology, biology, and medicine. These approaches are used to interpret and apply vast amounts of biological data generated from basic research to some of today’s key challenges in the biomedical, environmental, and agricultural sciences. With more than 240 highly trained multidisciplinary, international personnel, research at the institute involves collaboration in diverse disciplines such as mathematics, computer science, biology, plant pathology, biochemistry, systems biology, statistics, economics, synthetic biology, and medicine. The large amounts of data generated by this approach are analyzed and interpreted to create new knowledge that is disseminated to the world’s scientific, governmental, and wider communities.



Tiffany Trent


Published by Tiffany Trent, July 08, 2011