Silke Hauf studied medicine in Germany and France, with additional training at hospitals in China and the United States. After graduation, she started basic research in cell biology, and worked from 1999 to 2003 with Jan-Michael Peters at the Institute of Molecular Pathology (IMP) in Vienna, and from 2003 to 2005 with Yoshinori Watanabe at the University of Tokyo. From 2005 on, she lead a Max Planck Research Group in Tuebingen, Germany, from where she moved to Virginia Tech in 2014.
Her team studies the mechanisms that make cell division a highly reliable process. The group combines quantitative live cell imaging, molecular genetics and biochemical wet lab methods with computational modeling.