- Fellow and Associate Professor
- Associate Professor, Biological Sciences
Dr. Finkielstein is Associate Professor of Cell and Molecular Biology in the Department of Biological Sciences at Virginia Tech, Director of the Integrated Cellular Responses Laboratory, and Member of the Board of Directors of the Virginia Breast Cancer Foundation.
Born in Buenos Aires, Argentina, Dr. Carla Finkielstein received her Ph.D. in Molecular Biology from the School of Natural Sciences, University of Buenos Aires, a top-ranked University in Latin America. Later, Dr. Finkielstein pursued postdoctoral studies in the United States in two distinct, yet related, areas of research: cell and molecular biology and structural biology. She initiated her studies as Research Associate at the Howard Hughes Medical Institute, University of Colorado Comprehensive Cancer Center at both the Department of Pharmacology and later in Biochemistry and Molecular Biology.
Dr. Finkielstein has more than fifteen years experience as an accomplished scholar, teacher, and researcher. She founded the Integrated Cellular Responses Laboratory (ICRL) at Virginia Tech where her group works to understand the contribution of environmental factors on breast cancer initiation and progression.
Dr. Finkielstein has received numerous awards and recognitions over her lengthily career including the L.Chely Award to the Best PhD thesis, the Howard Hughes Institute Fellowship for Research, the American Heart Association PostDoctoral fellowship, the Karin Noss scholarship for research advocacy in Breast Cancer, the Susan G. Komen Award for Junior Investigators, and the most prestigious US award to a junior independent researcher: the National Science Foundation CAREER Award. Dr. Finkielstein’s research has been presented in conferences around the world and she has been presented with the Minority Scholar Award in Cancer Research from the American Association for Cancer Research that recognize rising minority researchers in the field. Dr. Finkielstein is a member of several professional associations including the American Association for Cancer Research, is a reviewer for many scientific journals within her field of specialization, is a panelist for the National Science Foundation and is an outspoken advocate for breast cancer awareness.
Her laboratory has produced over 40 publications and book chapters in the field, including articles in top journals such as Nature and Cell. In addition, She has filled and commercialized patents, trained over 120 undergraduate students that continued their graduate education in top and Ivy League Universities, and graduated numerous MSc and PhDs in the last years. Furthermore, Dr. Finkielstein has been running an international high school exchange program that has facilitated a new cultural and scientific experience to many Virginia and Argentinean students.
Gotoh T, Vila-Caballer M, Liu J, Schiffhauer S, Finkielstein CV. Association of the circadian factor Period 2 to p53 influences p53's function in DNA-damage signaling. Mol Biol Cell
. 2015;26:359–372. http://www.ncbi.nlm.nih.gov/pubmed/25411341
Xiao S, Brannon MK, Zhao X, et al. Tom1 Modulates Binding of Tollip to Phosphatidylinositol 3-Phosphate via a Coupled Folding and Binding Mechanism. Structure
. 2015;23:1910–1920. http://www.ncbi.nlm.nih.gov/pubmed/26320582
Gotoh T, Vila-Caballer M, Santos CS, Liu J, Yang J, Finkielstein CV. The circadian factor Period 2 modulates p53 stability and transcriptional activity in unstressed cells. Mol Biol Cell
. 2014;25:3081–3093. http://www.ncbi.nlm.nih.gov/pubmed/25103245
Gotoh T, Villa LM, Capelluto DG, Finkielstein CV. Regulatory pathways coordinating cell cycle progression in early Xenopus development. Results Probl Cell Differ
. 2011;53:171–199. http://www.ncbi.nlm.nih.gov/pubmed/21630146
Welsh JD, Charonko JJ, Salmanzadeh A, et al. Disabled-2 modulates homotypic and heterotypic platelet interactions by binding to sulfatides. Br J Haematol
. 2011;154:122–133. http://www.ncbi.nlm.nih.gov/pubmed/21539534
- University of Buenos Aires, Cell and Molecular Biology, Ph.D., 1998
- University of Buenos Aires - Argentina, Biological Sciences, B.S., 1992
- Associate Professor (Tenured) (08/2011 ? Present). Academic Institution: Department of Biological Sciences, Virginia tech. Field of study: Cellular and Molecular Biology. Research study: My laboratory investigates some of the basic mechanisms that regulate cell cycle transitions, the contribution of environmental cues to ensure timely progression throughout it, and how circadian and cell cycles are interlocked at the molecular level.
- Associate Professor (Affiliated) (01/2014 ? Present). Academic Institution: Department of Surgery, Virginia Tech-Carillion School of Medicine.
- Associate Professor, Faculty of Health Sciences (01/2013 ? Present). Academic Institution: Virginia Tech-Carillion School of Medicine.
- Associate Professor (Adjunct) (08/2009 ? Present). Academic Institution: Department of Biochemistry, Virginia tech.
- Assistant Professor (Tenure-Track) (08/2005 ? 08/2011). Academic Institution: Department of Biological Sciences, Virginia tech.
- PostDoctoral Fellow (12/2001 ? 07/2005). Field of study: Structural Biology. Research study: X-ray structural determination of cellular DNA replicases. Academic Institution: Department of Biochemistry and Molecular Genetics, School of Medicine, University of Colorado Health Sciences Center. Principal Investigator: Dr. X.S. Chen.
- Research Associate (07/1998 - 12/2001). Field of study: Cellular and Molecular Biology. Research Study: Cell cycle regulation and apoptosis in early Xenopus development. Academic Institution: Department of Pharmacology, Howard Hughes Medical Institute, University of Colorado Health Sciences Center. Principal Investigator: Dr. J.L. Maller.
- New Academic Leaders Workshop (08/2015 ? 11/2015). Institution: Office of the Executive Vice President and Provost, Virginia Tech
- Macromolecular Crystallography Course (10/2002). Institution: Cold Spring Harbor Laboratory. Instructors: Drs. W. Furey, G. Gilliland, A. McPherson, and J. Pflugrath.